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Volume 13, Issue 1, Pages 1-6 (February 2003)

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Bleeding disorders in pregnancy

Jane Strongf1

Abstract 

This article addresses bleeding disorders in pregnancy. It is divided into three sections: maternal and fetal thrombocytopenia, thrombotic microangiopathies and inherited bleeding disorders. The section on maternal and fetal thrombocytopenia covers gestational thrombocytopenia, thrombocytopenia secondary to hypertensive disorders of pregnancy, immune thrombocytopenia and neonatal alloimmune thrombo-cytopenia. The section on thrombotic microangiopathies covers HELLP (Haemolysis, Elevated Liver enzymes and Low Platelets) syndrome, thrombotic thrombocytopenic purpura and disseminated intravascular coagulation. The section on inherited bleeding disorders covers von Willebrands disease, haemophilia A and B, factor XI deficiency and acquired haemophilia.

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Abstract

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FURTHER READING

1. 1 Giangrande P LF. Management of pregnancy in carriers of haemophilia. Haemophilia. 1998;4:779–784. MEDLINE

2. 2 Gill KK, Kelton JG. Management of idiopathic thrombocytopenic purpura in pregnancy. Semin Hematol. 2000;37:275–289. Abstract | Full-Text PDF (1416 KB) | CrossRef

3. 3 Kadir RA. Women and inherited bleeding disorders: pregnancy and delivery. Semin Hematol. 1999;36:28–35. MEDLINE

4. 4 Kelton JG. Thrombocytopenia in pregnancy. Hematology. The American Society of Hematology Education Program Hand-book. New York: American Society of Hematology; 1999; p. 490–497.

5. 5 McCrae KR, Cines DB. Thrombotic microangiopathy during pregnancy. Semin Hematol. 1997;34:148–158. MEDLINE

6. 6 Sainio S, Teramo K, Kekomaki R. Prenatal treatment of severe fetomaternal alloimmune thrombocytopenia. Transf Med. 1999;9:321–330.

Department of Haematology, University Hospital, Derby Road, Nottingham, NG7 2UH, UK

f1 Correspondence to: JS. Tel.: 0115 875 4625; Fax: 0115 970 9186; E-mail: Jane.strong@mail.qmcuh-tr.trent.nhs.uk

PII: S0957-5847(03)90300-3

doi:10.1054/cuog.2003.0300

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